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One Shot Concentrates

New One Shots from the EJM Mix Team
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One Shot Concentrates

One Shots are flavor concentrates that are premixed to be a complete recipe. They offer a quick and convenient way to mix since all the guesswork of the recipe is removed. Seasoned or new mixers can benefit from the time saving, easy cleanup, and convenience of a completed recipe that One Shots prov

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New MixLife Show!  #vaping 

New MixLife Show! #vaping 

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New MixLife Show! #vaping

 

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Recipe – Stormy Weather – Flavor-Pro

Flavor Notes — FlavourArt – Juicy Strawberry – Flavor-Pro

New Flavor Notes on FlavourArt Juicy Strawberry – Two Recipes included. http://ow.ly/bzm330gcc4Z

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Flavor Notes — FlavourArt – Juicy Strawberry – Flavor-Pro

Flavor Notes — FlavourArt – Juicy Strawberry October 28, 2017 Jennifer Jarvis Featured, FlavourArt 0 The Strawberry Most of Us Have Been Waiting…

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Your sense of smell changes throughout the day - Futurity

Your sense of smell changes throughout the day – Futurity

Your sense of smell changes throughout the day
Smell sensitivity varies over the course of a day, new research suggests.

The pattern, according to the data collected by studying 37 teens, tracks with the body’s internal day-night cycle, or circadian rhythm.

“This finding is very important for olfactory perception science,” says Rachel Herz, lead author of the study and an adjunct assistant professor of psychiatry and human behavior at the Warren Alpert Medical School of Brown University. “This hadn’t been known before and this is the first clear, direct evidence.”

Around the circadian cycle, either by degrees or time of day, research subjects showed patterns in when their smell sensitivity peaked. Dots show the peak circadian degree, or time equivalent, for each subject. The purple area shows the average. The further dots are from the center, the greater the degree of sensitivity change at the peak. (Credit: Herz et al./Brown)
As one of the five senses, smell is an important ability, Herz notes, not only for experiencing and enjoying the world, but also for receiving information about danger, such as nearby fire or spoiled food, and for basic functions like eating. Changes in the sense during the day can affect all these capabilities.

Herz, an expert in the sense of smell, made the findings in collaboration with sleep expert Mary Carskadon, a professor of psychiatry and human behavior. Carskadon is conducting a larger study with a hypothesis that circadian timing and sleep habits may affect the eating habits of teens, potentially contributing to obesity.

Smell is associated with food consumption, notes Herz—who has authored the upcoming book Why You Eat What You Eat (W. W. Norton & Company, 2017)—so the researchers devised an experiment to determine whether smell varies with circadian rhythm.

Breaking sleep patterns

To conduct the study, the researchers asked the 21 boys and 16 girls, all between ages 12 and 15, to sleep on a fixed schedule for two weeks before reporting to the Bradley Hospital sleep lab. After an adaptation night in the lab, the teens began a week of 28-hour days where their sleep was shifted four hours later each “night.”

All along, they lived indoors in dim light, socializing and participating in fun activities with each other and staff members. The goal was to separate them temporarily from typical sleep disruptions and from external cues of circadian timing. In this way, Carskadon says, their inherent, internal circadian rhythms could be measured, as could the sensitivity of their sense of smell at all times throughout their rhythms (in addition to other measures, such as food intake).

Smell sensitivity (the z-score) rose and fell in accordance with circadian rhythm. (Credit: Herz et al./Brown)
The team measured circadian rhythm by detecting levels of the sleep-cueing hormone melatonin in their saliva. Melatonin secretion begins about an hour before the urge to sleep hits.

The researchers assessed smell sensitivity using “Sniffin’ Sticks,” a common test for measuring odor detection thresholds. Each time they used the sticks, the researchers could determine the threshold concentration of the odor that the teens could detect. Smell was assessed every three hours while teens were awake.

Peak smelling time

Individuals varied substantially in how much their smell sensitivity varied over a circadian cycle and in when it peaked. But there were clear patterns individually and overall. One was that the variance showed a circadian rhythm, and the other was that smell sensitivity was never strongest well into the “biological night,” or the period well after melatonin onset when people are most likely to be asleep and least likely to be eating. In clock terms, it’s from about 3 to 9 am.

“So we have 84 tests done on each child, and each one has a circadian phase associated with it,” Carskadon says. “There is a rhythm here, and it’s not flat or that you smell the same all the time. Your sense of smell changes in a predictable manner, though it’s not the same for every child.”

Smelling our food may make us gain weight

Carskadon says the findings should be of note to clinicians and researchers who seek to assess a patient’s sense of smell. The study suggests that sensitivity might be inherently higher at an afternoon appointment than in the early morning.

Herz notes that there could be implications for fire safety as well. A decade ago she and Carskadon had found that the sense of smell all but shuts down during sleep. Now there is evidence that the sense of smell is relatively weak during a quarter of the circadian cycle. This emphasizes, Herz says, the value of audible smoke alarms, since smell may be a poor indicator of that danger at least in the early morning hours.

Peak around 9 pm

On average, the peak of smell sensitivity was at the beginning of biological night, or about 9 pm for the teens.

Herz says she can only speculate about why smell sensitivity might peak, on average, in the late evening. From an evolutionary standpoint, it might be to ensure the greatest sense of satiety during the important end of day meal, it might be a way of increasing mating desire, or perhaps a way of scanning for nearby threats before bedding down for the evening.

For each individual, she says, knowing when during the day smell their sensitivity might peak could be a way of identifying the time when sensory experiences could be most pleasant.

For less ancient health concerns, however, Carskadon says more data from the experiments is coming to help the team determine whether the circadian fluctuations of smell sensitivity help determine food choices and eating behaviors among teens.

“The sense of smell changes across the 24 hours of the day,” Carskadon says. “We don’t know if that difference will affect what or how people eat. There is more to come.”

There’s no scientific proof that our sense of smell stinks

The researchers report their findings in the journal Chemical Senses.

A National Institutes of Health grant funded the research, and the Periodic Breathing Foundation and Craig Cogut funded the participation of student research apprentices.

Source: Brown University

The post Your sense of smell changes throughout the day appeared first on Futurity.
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Your sense of smell changes throughout the day – Futurity

 

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Kopel Line from MXR CollectionCredit to @forever_in_the_klouds_2 : The KOPEL lin...

Kopel Line from MXR CollectionCredit to @forever_in_the_klouds_2 : The KOPEL lin…

Kopel Line from MXR Collection

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Credit to @forever_in_the_klouds_2 : The KOPEL line from the MXR COLLECTION from @underground.labs gourmet eliquids at affordable prices .

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Sweet Summer Chilled 30ml by Apexified

Sweet Summer Chilled 30ml by Apexified

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Sweet Summer Chilled 30ml by Apexified

Sweet Summer Chilled 30ml by Apexified

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Ckemist Original: Mango Bear - e-liquid-recipes.com

Ckemist Original: Mango Bear – e-liquid-recipes.com

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Ckemist Original: Mango Bear – e-liquid-recipes.com

7.00% 27 Bears (SL) (CAP) * 1.00% Phillipine Mango (TPA) * 3.00% Sweet Mango (Cap) * 1.50% Sweetener (Sucralose) (TPA) * The Hype Juice you crave. Adjust Sweetener to tastes. Subs: PM can be subbed for FLV Mango or INW Mango .5%

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If you have any friends who own shops in Canada please let them know about our c...

If you have any friends who own shops in Canada please let them know about our c…

If you have any friends who own shops in Canada please let them know about our commercial line MXR Collection

Kopel doing his thing in the trees.

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Credit to @foster.jennifer21 : Sakura by kopel @underground.labs mxr collection
A sweet cherry blossom candy, with hints of hibiscus tea and raspberry. All topped off with a sweet powdered sugar finish that’s sure to satisfy the discerning sweet tooth.

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eJuice Recipe Idea – Klove by CheebaSteeba – Flavorah FLV

eJuice Recipe Idea – Klove by CheebaSteeba – Flavorah FLV

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eJuice Recipe Idea – Klove by CheebaSteeba – Flavorah FLV

Recipe Spotlight: Klove by CheebaSteeba.

Check out our blog post for more details.

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